In line with our findings, loss of the intracellular cholesterol carrier Niemann-Pick C1 (NPC1), which results in abnormal late endosomal/lysosomal lipid storage, has been shown to enhance the phagocytic capacity of microglia, increasing the uptake of myelin debris and A [60]
Biomarkers of oxidative stress are significantly elevated in Down syndrome
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Sinha RA, Singh BK, Zhou J, Wu Y, Farah BL, Ohba K, et al
